Kainic Acid [kyselina kainová]
- Terms
-
kainát
-
Digenic Acid
Kainate
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
- Annotation
- an antinematodal agent & excitatory amino acid agonist
- DUI
- D007608 MeSH Browser
- CUI
- M0011891
- CAS
- 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-
- Previous indexing
- Pyrrolidines (1966-1977)
- History note
- 86(78); was see under PYRROLIDINES 1978-85
- Public note
- 86; was see under PYRROLIDINES 1978-85
Allowable subheadings
- AD
- administration & dosage 24
- AE
- adverse effects 11
- AG
- agonists
- AA
- analogs & derivatives 8
- AN
- analysis 4
- AI
- antagonists & inhibitors 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 1
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology 21
- PO
- poisoning 1
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity 16
- UR
- urine