receptor leukemického inhibičního faktoru - alfa-podjednotka [Leukemia Inhibitory Factor Receptor alpha Subunit]

tematický
1
Termíny

antigen CD118
antigeny CD118
receptor pro leukemický inhibiční faktor - alfa-podjednotka
receptor pro LIF - alfa-podjednotka

 

Antigens, CD118
CD118 Antigen
CD118 Antigens
LIF Receptor alpha Subunit

Perzistentní odkaz   https://www.medvik.cz/link/D053680
Definice

A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.

DUI
D053680 MeSH Prohlížeč
CUI
M0495573
Historická pozn.
2007
Veřejná pozn.
2007

D Chemikálie a léčiva
D12.776 proteiny 2 575
D12.776.543 membránové proteiny 849
D12.776.543.750.705 receptory imunologické 129
D12.776.543.750.705.852 receptory cytokinové 81
D12.776.543.750.705.852.583 receptory OSM-LIF 1
D12.776.543.750.705.852.583.500 cytokinový receptor gp130 7
D12.776.543.750.750 receptory peptidů 21
D12.776.543.750.750.400 receptory růstových faktorů 29
D12.776.543.750.750.400.550 receptory faktorů růstu nervů 5
D12.776.543.750.750.400.550.250 receptor ciliárního neurotrofického faktoru
D12.776.543.750.750.400.550.250.500 cytokinový receptor gp130 7