Lymphocyte Culture Test, Mixed [test smíšené lymfocytární kultury]
- Terms
-
leukocytové kultury smíšené - test
smíšená leukocytární reakce
test MLC
-
Leukocyte Culture Test, Mixed
Mixed Leukocyte Culture Test
Mixed Leukocyte Reaction
Mixed Lymphocyte Culture Test
Mixed Lymphocyte Reaction
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
- Annotation
- NIM
- DUI
- D007959 MeSH Browser
- CUI
- M0012408
- Previous indexing
- Histocompatibility Testing (1968-1972); Leukocytes (1966-1972)
- History note
- 93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
- Online note
- use LYMPHOCYTE CULTURE TEST, MIXED to search LEUKOCYTE CULTURE TEST, MIXED 1973-92
- Public note
- 93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
Allowable subheadings
- AE
- adverse effects
- CL
- classification
- EC
- economics
- ES
- ethics
- HI
- history
- IS
- instrumentation
- MT
- methods 2
- MO
- mortality
- ST
- standards
- SN
- statistics & numerical data
- TD
- trends
- VE
- veterinary