COP9 Signalosome Complex [COP9 signalozom]

topical
Terms

COP9 signalosom
COP9 signalozom (CSN)
COP9 signalozom, podjednotka 1
COP9 signalozom, podjednotka 2
COP9 signalozom, podjednotka 3
COP9 signalozom, podjednotka 4
COP9 signalozom, podjednotka 5
COP9 signalozom, podjednotka 6
COP9 signalozom, podjednotka 7A
COP9 signalozom, podjednotka 7B
COP9 signalozom, podjednotka 8
FUSCA-protein 11
Sgn3

 

Constitutive Photomorphogenesis 9 Signalosome
Constitutive Photomorphogenesis 9 Signalsome
COP9 Signalosome (CSN)
COP9 Signalosome Subunit 1
COP9 Signalosome Subunit 2
COP9 Signalosome Subunit 3
COP9 Signalosome Subunit 4
COP9 Signalosome Subunit 5
COP9 Signalosome Subunit 6
COP9 Signalosome Subunit 7A
COP9 Signalosome Subunit 7B
COP9 Signalosome Subunit 8
COP9 Signalsome
FUSCA Protein 11
G Protein Pathway Suppressor 1
Sgn3
Signalosome Subunit 3

Persistent link   https://www.medvik.cz/link/D000075686
Definition

A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits (CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where it controls gene transcription in response to light.

DUI
D000075686 MeSH Browser
CUI
M0234074
History note
2018 (1995); for COP9 SIGNALOSOME SUBUNIT 3 use SIGNALOSOME SUBUNIT 3 1998-2017
Public note
2018; COP9 SIGNALOSOME COMPLEX was indexed under PEPTIDE HYDROLASES and MULTIPROTEIN COMPLEXES 2006-207; under PROTEINS 1995-2005; and under PLANT PROTEINS 1995-1999; for COP9 SIGNALOSOME SUBUNIT 3 see SIGNALOSOME SUBUNIT 3 1998-2017; SIGNALOSOME SUBUNIT 3 was indexed under NUCLEAR PROTEINS and PROTEIN KINASES 1998-2017

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.049 Amyloid 166
D05.500.099 Apoptosomes 2
D05.500.117 Axin Signaling Complex 1
D05.500.135 Calcifying Nanoparticles 1
D05.500.139 COP9 Signalosome Complex
D05.500.142 Dynactin Complex 1
D05.500.149 Dystrophin-Associated Protein Complex 1
D05.500.199 Endosomal Sorting Complexes Required for Transport 8
D05.500.224 Inflammasomes 27
D05.500.299 Lactose Synthase
D05.500.337 Mechanistic Target of Rapamycin Complex 1 18
D05.500.356 Mechanistic Target of Rapamycin Complex 2 3
D05.500.374 Mediator Complex 5
D05.500.437 Mitochondrial Permeability Transition Pore 8
D05.500.469 Mitochondrial Precursor Protein Import Complex Proteins
D05.500.500 Molecular Motor Proteins 11
D05.500.562 Multienzyme Complexes 40
D05.500.672 NF-kappa B 220
D05.500.781 Polycomb-Group Proteins 7
D05.500.890 Protein Translocation Systems
D05.500.918 Shelterin Complex 2
D05.500.945 Troponin 266
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 549
D08.811.037 Deubiquitinating Enzymes 5
D08.811.037.750 Ubiquitin-Specific Proteases 10
D08.811.037.750.250 COP9 Signalosome Complex
D08.811.037.750.500 Tumor Necrosis Factor alpha-Induced Protein 3 2
D08.811.037.750.750 Ubiquitin-Specific Peptidase 7
D08.811.277 Hydrolases 475
D08.811.277.656 Peptide Hydrolases 559
D08.811.277.656.300 Endopeptidases 211
D08.811.277.656.300.887 Ubiquitin-Specific Proteases 10
D08.811.277.656.300.887.375 COP9 Signalosome Complex
D08.811.277.656.300.887.750 Tumor Necrosis Factor alpha-Induced Protein 3 2
D08.811.277.656.300.887.875 Ubiquitin-Specific Peptidase 7

Alien protein, Drosophila Chemical MeSH Browser

COP9 signalosome subunit 5, Arabidopsis Chemical MeSH Browser

COPS2 protein, human Chemical MeSH Browser

COPS3 protein, human Chemical MeSH Browser

COPS4 protein, human Chemical MeSH Browser

COPS5 protein, human Chemical MeSH Browser

COPS6 protein, human Chemical MeSH Browser

COPS7A protein, human Chemical MeSH Browser

COPS8 protein, human Chemical MeSH Browser

CSN1 protein, Arabidopsis Chemical MeSH Browser

CSN2 protein, Arabidopsis Chemical MeSH Browser

CSN4 protein, Drosophila Chemical MeSH Browser

CSN5 protein, Drosophila Chemical MeSH Browser

CSN6 protein, Drosophila Chemical MeSH Browser

CSN6B protein, Arabidopsis Chemical MeSH Browser

CSN7 protein, Arabidopsis Chemical MeSH Browser

CSN7 protein, Drosophila Chemical MeSH Browser

CSN8 protein, Drosophila Chemical MeSH Browser

Cops2 protein, mouse Chemical MeSH Browser

Cops2 protein, rat Chemical MeSH Browser

Cops3 protein, mouse Chemical MeSH Browser

Cops5 protein, mouse Chemical MeSH Browser

Cops6 protein, mouse Chemical MeSH Browser

Cops6 protein, zebrafish Chemical MeSH Browser

Cops8 protein, mouse Chemical MeSH Browser

Csn5 protein, S pombe Chemical MeSH Browser

FUS11 protein, Arabidopsis Chemical MeSH Browser

GPS1 protein, human Chemical MeSH Browser

Gps1 protein, rat Chemical MeSH Browser

Rri1 protein, S cerevisiae Chemical MeSH Browser

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