Axin Signaling Complex [signální komplex axin]

topical
1
Terms

axin signální komplex proteinů
beta katenin destrukční komplex

 

Axin Signaling Complex Proteins
beta-Catenin Destruction Complex

Persistent link   https://www.medvik.cz/link/D060465
Definition

A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.

DUI
D060465 MeSH Browser
CUI
M0554162
History note
2012
Public note
2012

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.049 Amyloid 166
D05.500.099 Apoptosomes 2
D05.500.117 Axin Signaling Complex 1
D05.500.117.249 Adenomatous Polyposis Coli Protein 13
D05.500.117.500 Axin Protein 3
D05.500.117.750 Casein Kinase I 7
D05.500.117.875 Glycogen Synthase Kinase 3 23
D05.500.135 Calcifying Nanoparticles 1
D05.500.139 COP9 Signalosome Complex
D05.500.142 Dynactin Complex 1
D05.500.149 Dystrophin-Associated Protein Complex 1
D05.500.199 Endosomal Sorting Complexes Required for Transport 8
D05.500.224 Inflammasomes 27
D05.500.299 Lactose Synthase
D05.500.337 Mechanistic Target of Rapamycin Complex 1 18
D05.500.356 Mechanistic Target of Rapamycin Complex 2 3
D05.500.374 Mediator Complex 5
D05.500.437 Mitochondrial Permeability Transition Pore 8
D05.500.469 Mitochondrial Precursor Protein Import Complex Proteins
D05.500.500 Molecular Motor Proteins 11
D05.500.562 Multienzyme Complexes 40
D05.500.672 NF-kappa B 220
D05.500.781 Polycomb-Group Proteins 7
D05.500.890 Protein Translocation Systems
D05.500.918 Shelterin Complex 2
D05.500.945 Troponin 266
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.008 3',5'-Cyclic-AMP Phosphodiesterases 12
D12.776.476.009 3',5'-Cyclic-GMP Phosphodiesterases 2
D12.776.476.011 Activating Transcription Factor 6 3
D12.776.476.024 Adaptor Proteins, Signal Transducing 182
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.075 Apoptosis Regulatory Proteins 79
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.081.249 Adenomatous Polyposis Coli Protein 13
D12.776.476.081.500 Axin Protein 3
D12.776.476.081.875 Glycogen Synthase Kinase 3 23
D12.776.476.156 Circadian Rhythm Signaling Peptides and Proteins 11
D12.776.476.175 Cold Shock Proteins and Peptides 3
D12.776.476.225 Cyclin-Dependent Kinase Inhibitor Proteins 44
D12.776.476.262 Cyclins 112
D12.776.476.265 Disks Large Homolog 4 Protein 1
D12.776.476.325 GTP-Binding Protein Regulators 16
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 30
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.383 Inhibitor of Growth Protein 1
D12.776.476.387 Intracellular Calcium-Sensing Proteins 2
D12.776.476.410 Mesothelin 2
D12.776.476.420 Methyl-Accepting Chemotaxis Proteins
D12.776.476.445 Mitogen-Activated Protein Kinase Phosphatases 1
D12.776.476.534 Mucin-4 5
D12.776.476.539 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.476.543 Olfactory Marker Protein
D12.776.476.555 Phosphatidylethanolamine Binding Protein
D12.776.476.556 Phosphatidylinositol 3-Kinases 126
D12.776.476.557 Phosphoinositide Phospholipase C 2
D12.776.476.559 Phosphoprotein Phosphatases 23
D12.776.476.561 Protein Phosphatase Inhibitory Proteins
D12.776.476.563 Protein Serine-Threonine Kinases 273
D12.776.476.564 Protein Tyrosine Phosphatases 27
D12.776.476.568 Protein-Tyrosine Kinases 622
D12.776.476.590 PTEN Phosphohydrolase 50
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.700 SAP90-PSD95 Associated Proteins
D12.776.476.800 Secreted Frizzled-Related Proteins
D12.776.476.900 Sirtuins 20
D12.776.476.932 Tuberous Sclerosis Complex 1 Protein 7
D12.776.476.935 Tuberous Sclerosis Complex 2 Protein 10
D12.776.476.938 Tumor Necrosis Factor alpha-Induced Protein 3 2
D12.776.476.941 Tumor Protein, Translationally-Controlled 1

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