Levodopa [levodopa]
- Terms
-
3-Hydroxy-L-tyrosine
Dopaflex
Dopar
L-3,4-Dihydroxyphenylalanine
L-Dopa
Larodopa
Levopa
The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
- DUI
- D007980 MeSH Browser
- CUI
- M0012434
- Previous indexing
- Dopa (1966-1974)
- History note
- 75; was see DOPA 1972-74
- Online note
- search DOPA 1972-74
- Public note
- 75; was see DOPA 1972-74
Allowable subheadings
- AD
- administration & dosage 103
- AE
- adverse effects 69
- AG
- agonists 1
- AA
- analogs & derivatives 3
- AN
- analysis 2
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 1
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 3
- CL
- classification 1
- DF
- deficiency 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 2
- IM
- immunology 0
- IP
- isolation & purification 2
- ME
- metabolism 5
- PK
- pharmacokinetics 17
- PD
- pharmacology 48
- PH
- physiology 2
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 154
- TO
- toxicity 0
- UR
- urine 0