Inactivation, Metabolic [metabolická inaktivace]

topical
114
Terms

metabolická detoxikace léků
metabolická inaktivace léků

 

Detoxication, Drug, Metabolic
Detoxification, Drug, Metabolic
Drug Detoxication, Metabolic
Metabolic Detoxication, Drug
Metabolic Detoxification, Drug
Metabolic Drug Inactivation

Persistent link   https://www.medvik.cz/link/D008658
Definition

Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes those metabolic transformations that make the substance more soluble for faster renal excretion.

Annotation
restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab
DUI
D008658 MeSH Browser
CUI
M0590700
History note
2015 (1970); use BIOTRANSFORMATION 1970-1979
Public note
2015; see METABOLIC DETOXICATION, DRUG 1980-2014; see BIOTRANSFORMATION 1970-1979

Allowable subheadings

DE
drug effects 11
GE
genetics 9
IM
immunology 1
PH
physiology 18
RE
radiation effects 1

G Phenomena and Processes
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G03.171 Biotransformation 794
G03.171.224 Activation, Metabolic 12
G03.171.450 Inactivation, Metabolic 114
G03.171.450.500 Metabolic Detoxication, Phase I 7
G03.171.450.750 Metabolic Detoxication, Phase II 6
G03.787 Pharmacokinetics 750
G03.787.225 Biotransformation 794
G03.787.225.224 Activation, Metabolic 12
G03.787.225.450 Inactivation, Metabolic 114
G03.787.225.450.500 Metabolic Detoxication, Phase I 7
G03.787.225.450.750 Metabolic Detoxication, Phase II 6
G07 Physiological Phenomena 176
G07.690 Pharmacological and Toxicological Phenomena 59
G07.690.725 Pharmacokinetics 750
G07.690.725.225 Biotransformation 794
G07.690.725.225.224 Activation, Metabolic 12
G07.690.725.225.450 Inactivation, Metabolic 114
G07.690.725.225.450.500 Metabolic Detoxication, Phase I 7
G07.690.725.225.450.750 Metabolic Detoxication, Phase II 6

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