Monoamine Oxidase [monoaminoxidasa]
- Terms
-
MAO
MAO typu A
MAO typu B
monoaminooxidáza
monoaminoxidasa A
monoaminoxidasa B
monoaminoxidáza A
monoaminoxidáza B
tyraminoxidasa
tyraminoxidáza
-
Amine Oxidase (Flavin-Containing)
MAO
MAO-A
MAO-B
Monoamine Oxidase A
Monoamine Oxidase B
Type A Monoamine Oxidase
Type B Monoamine Oxidase
Tyramine Oxidase
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
- DUI
- D008995 MeSH Browser
- CUI
- M0014026
- CAS
- Amine:oxygen oxidoreductase (deaminating) (flavin-containing)
- History note
- 63; for TYRAMINE OXIDASE use MONOAMINE OXIDASE (NM) 1980-98
- Public note
- 63; TYRAMINE OXIDASE was indexed under AMINE OXIDOREDUCTASES 1980-98
Combination
- antagonists & inhibitors
- Monoamine Oxidase Inhibitors
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 6
- BI
- biosynthesis 1
- BL
- blood 3
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 4
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 8
- EC
- economics 0
- GE
- genetics 5
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 1
- ME
- metabolism 40
- PK
- pharmacokinetics 0
- PD
- pharmacology 1
- PH
- physiology 9
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0