Naltrexone [naltrexon]
- Terms
-
Antaxone
Celupan
EN-1639A
Nalorex
Naltrexone Hydrochloride
Nemexin
ReVia
Trexan
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
- DUI
- D009271 MeSH Browser
- CUI
- M0014445
- CAS
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
- Previous indexing
- Cyclopropanes (1973-1975); Morphinans (1973-1974); Naloxone/analogs & derivatives (1975)
- History note
- 1986 (1976)
- Public note
- 1986; NALTREXONE was indexed under NALOXONE 1976-1985
Allowable subheadings
- AD
- administration & dosage 42
- AE
- adverse effects 18
- AG
- agonists
- AA
- analogs & derivatives 8
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics 2
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics 8
- PD
- pharmacology 45
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 89
- TO
- toxicity
- UR
- urine
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