An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.

DUI

D009621 MeSH Prohlížeč

CUI

M0014939

CAS

2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-, methyl ester, (2R-(2alpha,3beta,4alpha,5beta,6alpha,11beta,13alpha,14alpha))-

Předchozí užití

Antibiotics (1966); Glycosides (1966-1975); Antibiotics, Antineoplastic (1967-1975); Naphthacenes (1966-1975)

Historická pozn.

91(76); was see under DAUNORUBICIN 1981-90; was see under NAPHTHACENES 1976-80

Veřejná pozn.

91; was see under DAUNORUBICIN 1981-90; was see under NAPHTHACENES 1976-80