An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)

DUI

D009627 MeSH Prohlížeč

CUI

M0014947

CAS

8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-

Předchozí užití

Quinolines (1966-1968); Isoquinolines (1969-1977)

Historická pozn.

86(78); was see under ISOQUINOLINES 1978-85

Veřejná pozn.

86; was see under ISOQUINOLINES 1978-85