Phenobarbital [fenobarbital]

topical
199
Terms

Gardenal
Hysteps
Luminal
phenobarbitalum natricum
sodná sůl fenobarbitalu

 

Gardenal
Hysteps
Luminal
Phenemal
Phenobarbital Sodium
Phenobarbital, Monosodium Salt
Phenobarbitone
Phenylbarbital
Phenylethylbarbituric Acid

Persistent link   https://www.medvik.cz/link/D010634
Definition

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

DUI
D010634 MeSH Browser
CUI
M0016514
CAS
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-

Allowable subheadings

AD
administration & dosage 37
AE
adverse effects 20
AG
agonists
AA
analogs & derivatives 4
AN
analysis 7
AI
antagonists & inhibitors
BL
blood 7
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 2
CL
classification
EC
economics
HI
history
IM
immunology 1
IP
isolation & purification 3
ME
metabolism 10
PK
pharmacokinetics 12
PD
pharmacology 41
PO
poisoning 2
RE
radiation effects
ST
standards 1
SD
supply & distribution
TU
therapeutic use 38
TO
toxicity 6
UR
urine 2

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 190
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.742 Pyrimidines 982
D03.383.742.698 Pyrimidinones 75
D03.383.742.698.253 Barbiturates 201
D03.383.742.698.253.077 Amobarbital 13
D03.383.742.698.253.150 Barbital 5
D03.383.742.698.253.317 Hexobarbital 12
D03.383.742.698.253.434 Mephobarbital
D03.383.742.698.253.488 Methohexital 7
D03.383.742.698.253.500 Murexide
D03.383.742.698.253.593 Pentobarbital 104
D03.383.742.698.253.650 Phenobarbital 199
D03.383.742.698.253.650.700 Primidone 25
D03.383.742.698.253.762 Secobarbital 1
D03.383.742.698.253.800 Thiobarbiturates 19
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D09 Carbohydrates 724
D10 Lipids 2 528
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 045
D27 Chemical Actions and Uses 374

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