fenytoin [Phenytoin]
- Termíny
-
difenylhydantoin
difenylthiohydantoin
-
5,5-Diphenylhydantoin
5,5-diphenylimidazolidine-2,4-dione
Antisacer
Difenin
Dihydan
Dilantin
Diphenylhydantoin
Epamin
Epanutin
Fenitoin
Hydantol
Phenhydan
Phenytoin Sodium
Sodium Diphenylhydantoinate
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
- DUI
- D010672 MeSH Prohlížeč
- CUI
- M0016580
- CAS
- 2,4-Imidazolidinedione, 5,5-diphenyl-
- Historická pozn.
- 78; was DIPHENYLHYDANTOIN 1963-77
- Online pozn.
- use PHENYTOIN to search DIPHENYLHYDANTOIN 1966-77
- Veřejná pozn.
- 78; was DIPHENYLHYDANTOIN 1963-77
Povolená podhesla
- AG
- agonisté 0
- AA
- analogy a deriváty 1
- AN
- analýza 7
- AI
- antagonisté a inhibitory 0
- AD
- aplikace a dávkování 32
- CS
- chemická syntéza 0
- CH
- chemie 3
- HI
- dějiny 0
- EC
- ekonomika 0
- PK
- farmakokinetika 10
- PD
- farmakologie 25
- IM
- imunologie 0
- IP
- izolace a purifikace 0
- CL
- klasifikace 0
- BL
- krev 13
- ME
- metabolismus 6
- UR
- moč 1
- CF
- mozkomíšní mok 0
- ST
- normy 0
- PO
- otrava 2
- AE
- škodlivé účinky 36
- TU
- terapeutické užití 44
- TO
- toxicita 8
- RE
- účinky záření 0
- SD
- zásobování a distribuce 1