Poly(ADP-ribose) Polymerases [poly(ADP-ribosa)polymerasy]
topical
63
- Terms
-
PARP
poly(ADP-ribóza)-polymerázy
poly(ADP-ribóza)polymeráza
poly(ADP-ribóza)polymerázy
poly(ADP-ribóza)transferáza
polymerasa poly(ADP-ribosy)
synthasa poly(ADP-ribosy)
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ADP-Ribosyltransferase (Polymerizing)
PARP Polymerase
Poly ADP Ribose Polymerase
Poly ADP Ribose Transferase
Poly ADP-Ribose Synthase
Poly(ADP-ribose) Polymerase
Poly(ADP-Ribose) Synthase
Poly(ADP-Ribose) Transferase
Poly(ADPR) Polymerase
Poly(ADPribose) Polymerase
Persistent link
https://www.medvik.cz/link/D011065
Definition
Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
- DUI
- D011065 MeSH Browser
- CUI
- M0017141
- CAS
- NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase
- Previous indexing
- NAD Nucleosidase (1975-1976); Nucleosidases (1966-1974)
- History note
- 2003 (1977); use NAD NUCLEOSIDASE 1975-1976
- Public note
- 2003; see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1977-1991, see NAD NUCLEOSIDASE 1975-1976
Combination
- antagonists & inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors
Allowable subheadings
- AD
- administration & dosage 5
- AE
- adverse effects 1
- AN
- analysis 1
- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 2
- EC
- economics 0
- GE
- genetics 10
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 0
- ME
- metabolism 29
- PK
- pharmacokinetics 1
- PD
- pharmacology 5
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 12
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs