Nedostatek proteinů v potravě se projevuje změnami adaptivních jaterních enzymů, zvýšenou hladinou ligáz aminokyselin a sníženou tvorbou močoviny (snižuje se tak ztráta dusíku močí). Závažný nedostatek proteinů poškozuje růst, imunitní odpověď, opravu a tvorbu enzymů a hormonů. Deficit proteinů může také nastat při příjmu nekvalitních bílkovin, kdy v jejich složení chybí jedna nebo více aminokyselin.

A nutritional condition produced by a deficiency of proteins in the diet, characterized by adaptive enzyme changes in the liver, increase in amino acid synthetases, and diminution of urea formation, thus conserving nitrogen and reducing its loss in the urine. Growth, immune response, repair, and production of enzymes and hormones are all impaired in severe protein deficiency. Protein deficiency may also arise in the face of adequate protein intake if the protein is of poor quality (i.e., the content of one or more amino acids is inadequate and thus becomes the limiting factor in protein utilization). (From Merck Manual, 16th ed; Harrison's Principles of Internal Medicine, 12th ed, p406)

Anotace

deficiency of dietary protein, not genetic defic of specific proteins; consider also PROTEIN-CALORIE MALNUTRITION

DUI

D011488 MeSH Prohlížeč

CUI

M0017855