Receptor, Epidermal Growth Factor [receptor EGF]
- Terms
-
c-erbB1
EGFR
HER1
receptor epidermálního růstového faktoru
-
c-erbB-1 Protein
EGF Receptor
Epidermal Growth Factor Receptor
Epidermal Growth Factor Receptor Kinase
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
erbB-1 Proto-Oncogene Protein
Proto-oncogene c-ErbB-1 Protein
Receptor Tyrosine-protein Kinase erbB-1
Receptor, EGF
Receptor, ErbB-1
Receptor, TGF-alpha
Receptor, Transforming-Growth Factor alpha
Receptor, Urogastrone
TGF-alpha Receptor
Transforming Growth Factor alpha Receptor
Urogastrone Receptor
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
- DUI
- D011958
- CUI
- M0018582
- RN
- EC 2.7.10.1
- Last active year
- 2018
- Previous indexing
- Urogastrone (1966-1981); Epidermal Growth Factor-Urogastrone (1982-1986); Epidermal Growth Factors (1977-1981); Receptors, Cell Surface (1973-1986)
- History note
- 2000(1987); for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, EPIDERMAL GROWTH FACTOR 1994-1999
- Public note
- 2000; see RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE 1978-1999; for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE see EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999