Receptors, LDL [LDL-receptory]
- Terms
-
LDL-receptor
receptor LDL
receptor pro LDL
receptory LDL
receptory pro LDL
-
LDL Receptor
LDL Receptors
LDL Receptors, Lipoprotein
Lipoprotein LDL Receptors
Low Density Lipoprotein Receptor
Low Density Lipoprotein Receptors
Receptors, Lipoprotein, LDL
Receptors, Low Density Lipoprotein
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
- DUI
- D011973 MeSH Browser
- CUI
- M0018606
- Previous indexing
- Receptors, Endogenous Substances (1973-1984); Lipoproteins, LDL (1972-1984)
- History note
- 85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92
- Online note
- use RECEPTORS, LDL to search LIPOPROTEINS, LDL RECEPTORS 1985-92
- Public note
- 85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92
Allowable subheadings
- AD
- administration & dosage
- AG
- agonists 1
- AN
- analysis 5
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood 2
- CH
- chemistry
- CL
- classification 1
- DF
- deficiency 4
- DE
- drug effects 9
- GE
- genetics 48
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification 1
- ME
- metabolism 13
- PH
- physiology 4
- RE
- radiation effects
- TU
- therapeutic use
- UL
- ultrastructure
AMG-220 Chemical MeSH Browser
LDLR protein, human Chemical MeSH Browser
LDLRAD3 protein, human Chemical MeSH Browser
LRP1B protein, human Chemical MeSH Browser
Ldlr protein, mouse Chemical MeSH Browser
Lrp1b protein, mouse Chemical MeSH Browser
Lrp1b protein, rat Chemical MeSH Browser
Lrp4 protein, rat Chemical MeSH Browser
Lsr protein, rat Chemical MeSH Browser
MALRD1 protein, human Chemical MeSH Browser
RME-2 protein, C elegans Chemical MeSH Browser
SAMD1 protein, human Chemical MeSH Browser
Sorl1 protein, mouse Chemical MeSH Browser
Sorl1 protein, rat Chemical MeSH Browser
VLDL receptor Chemical MeSH Browser
alpha-tocopherol receptor Chemical MeSH Browser
lipolysis-stimulated receptor Chemical MeSH Browser
low density lipoprotein receptor-related protein 1, zebrafish Chemical MeSH Browser
very low density lipoprotein receptor type II, human Chemical MeSH Browser