A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.

Annotation

does not refer to all sex hormones: refers to a specific protein in the blood binding only testosterone or estradiol; for other sex hormone-binding globulins consider ANDROGEN-BINDING PROTEIN & PROGESTERONE-BINDING GLOBULIN

DUI

D012738 MeSH Browser

CUI

M0019743

Previous indexing

Carrier Proteins (1971-1991); Glycoproteins (1974-1975); Beta Globulins (1974-1976); Protein Binding (1974-1975); Sex Hormones (1974-1976)

History note

77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92

Online note

use SEX HORMONE-BINDING GLOBULIN (NM) to search SEX-STEROID-BINDING PROTEIN 1981-91; use SEX HORMONE-BINDING GLOBULIN to search ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN 1977-92

Public note

77; SEX-STEROID-BINDING PROTEIN was indexed under CARRIER PROTEINS 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92