Somatostatin [somatostatin]
- Terms
-
somatostatin-14
SRIF
Stilamin
-
Cyclic Somatostatin
Somatofalk
Somatostatin-14
Somatostatin, Cyclic
Somatotropin Release-Inhibiting Factor
Somatotropin Release-Inhibiting Hormone
SRIH-14
Stilamin
A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
- DUI
- D013004 MeSH Browser
- CUI
- M0020152
- Previous indexing
- Somatotropin/antagonists & inhibitors (1973-1974); Somatotropin Releasing Hormone/antagonists & inhibitors (1974)
- History note
- 99
- Online note
- use SOMATOSTATIN to search SOMATOTROPIN RELEASE INHIBITING HORMONE 1975-84
- Public note
- 99
Allowable subheadings
- AD
- administration & dosage 99
- AE
- adverse effects 32
- AG
- agonists
- AA
- analogs & derivatives 259
- AN
- analysis 6
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis
- BL
- blood 13
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 6
- CL
- classification 3
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 4
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification 2
- ME
- metabolism 18
- PK
- pharmacokinetics 10
- PD
- pharmacology 66
- PH
- physiology 19
- PO
- poisoning
- RE
- radiation effects 1
- ST
- standards
- SD
- supply & distribution 1
- TU
- therapeutic use 220
- TO
- toxicity
- UR
- urine
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