A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

DUI

D013467 MeSH Browser

CUI

M0020810

CAS

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

Previous indexing

Benzene Derivatives (1968-1974); Benzene (1966-1967); Benzylidene Compounds (1975-1978); Indenes (1966-1978)

History note

90(79); was see under INDENES 1979-89

Public note

90; was see under INDENES 1979-89