A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

DUI

D013467 MeSH Prohlížeč

CUI

M0020810

CAS

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

Předchozí užití

Benzene Derivatives (1968-1974); Benzene (1966-1967); Benzylidene Compounds (1975-1978); Indenes (1966-1978)

Historická pozn.

90(79); was see under INDENES 1979-89

Veřejná pozn.

90; was see under INDENES 1979-89