T-Lymphocytes, Cytotoxic [cytotoxické T-lymfocyty]
- Terms
-
cytotoxické T lymfocyty
cytotoxické T-buňky
T-lymfocyty cytotoxické
TC1 lymfocyty
TC1-lymfocyty
TC2 lymfocyty
TC2-lymfocyty
-
Cell-Mediated Lympholytic Cells
Cytotoxic T Cells
Cytotoxic T Lymphocyte
Cytotoxic T-Lymphocytes
TC1 Cell
TC1 Cells
TC2 Cell
TC2 Cells
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
- Annotation
- if subpopulations are discussed, coordinate IM with T-LYMPHOCYTE SUBSETS (IM)
- DUI
- D013602 MeSH Browser
- CUI
- M0020989
- Previous indexing
- Cytotoxicity, Immunologic (1978-1982); T Lymphocytes (1973-1982)
- History note
- 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
- Online note
- use T-LYMPHOCYTES, CYTOTOXIC to search T LYMPHOCYTES, CYTOTOXIC 1983-89
- Public note
- 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
Allowable subheadings
- CH
- chemistry
- CL
- classification 2
- CY
- cytology 3
- DE
- drug effects 7
- EN
- enzymology 2
- IM
- immunology 56
- ME
- metabolism 6
- MI
- microbiology 1
- PS
- parasitology
- PA
- pathology 3
- PH
- physiology 16
- RE
- radiation effects
- TR
- transplantation 1
- UL
- ultrastructure
- VI
- virology