Cytolytic lymphocytes with the unique capacity of killing natural killer (NK)-resistant fresh tumor cells. They are INTERLEUKIN-2-activated NK cells that have no MAJOR HISTOCOMPATIBILITY COMPLEX restriction or need for antigen stimulation. LAK cells are used for ADOPTIVE IMMUNOTHERAPY in cancer patients.

Annotation

if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM)

DUI

D015979 MeSH Browser

CUI

M0024414

Previous indexing

Killer Cells, Natural (1982-1989)

History note

90

Public note

90