3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.

Anotace

do not confuse with THIAMIN TRIPHOSPHATASE; deficiency: coordinate THIAMINE TRIPHOSPHATE /defic (IM) with THIAMINE DEFICIENCY (IM)

DUI

D013838 MeSH Prohlížeč

CUI

M0021326

CAS

Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)-, inner salt, P,P',P''-trioxide

Předchozí užití

Organophosphorus Compounds (1971-1978); Thiamine (1966-1978)

Historická pozn.

91(79); was see under THIAMINE 1979-90

Veřejná pozn.

91; was see under THIAMINE 1979-90