Thiotepa [thiotepa]
- Terms
-
AI3-24916
Girostan
NSC-6396
Tespa
Tespamin
Thio-Tepa
Thiophosphamide
Triethylenethiophosphoramide
Tris(1-aziridinyl)phosphine Sulfide
A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
- DUI
- D013852 MeSH Browser
- CUI
- M0021343
- CAS
- Aziridine, 1,1',1''-phosphinothioylidynetris-
- History note
- 92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91
- Online note
- use THIOTEPA to search THIO-TEPA 1966-91
- Public note
- 92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91
Allowable subheadings
- AD
- administration & dosage 6
- AE
- adverse effects 3
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 7
- TO
- toxicity
- UR
- urine
thiotepa-glutathione conjugate Chemical MeSH Browser