Thiotepa [thiotepa]

topical
23
Terms

AI3-24916
Girostan
NSC-6396
Tespa
Tespamin
Thio-Tepa
Thiophosphamide
Triethylenethiophosphoramide
Tris(1-aziridinyl)phosphine Sulfide

Persistent link   https://www.medvik.cz/link/D013852
Definition

A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

DUI
D013852 MeSH Browser
CUI
M0021343
CAS
Aziridine, 1,1',1''-phosphinothioylidynetris-
History note
92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91
Online note
use THIOTEPA to search THIO-TEPA 1966-91
Public note
92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91

D Chemicals and Drugs
D02.705.672 Phosphoramides
D02.705.672.249 Hempa 2
D02.705.672.500 Phosphoramide Mustards
D02.705.672.875 Thiotepa 23
D03.383.097 Azirines 7
D03.383.097.217 Aziridines 17
D03.383.097.217.935 Triethylenephosphoramide 2
D03.383.097.217.935.960 Thiotepa 23

thiotepa-glutathione conjugate Chemical MeSH Browser