2-Acetylaminofluorene [2-acetylaminofluoren]

topical
6
Terms

2-AAF
acetylaminofluoren

 

2-AAF
2-Acetamidofluorene
2-Fluorenylacetamide
AAF, Aminofluorene
Acetylaminofluorene
Fluoren-2-ylacetamide
N-2-Fluorenylacetamide
N-Acetyl-2-Aminofluorene

Persistent link   https://www.medvik.cz/link/D015073
Definition

A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

DUI
D015073 MeSH Browser
CUI
M0023186
CAS
Acetamide, N-9H-fluoren-2-yl-
Previous indexing
Fluorenes (1966-1974); Acetamides (1971-1974)
History note
83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Online note
use 2-ACETYLAMINOFLUORENE to search ACETYLAMINOFLUORENE 1975-82
Public note
83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79

Allowable subheadings

AD
administration & dosage
AE
adverse effects 1
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity 3
UR
urine

D Chemicals and Drugs
D02 Organic Chemicals 391
D02.065 Amides 260
D02.065.064 Acetamides 133
D02.065.064.150 2-Acetylaminofluorene 6
D02.065.064.150.100 Acetoxyacetylaminofluorene 2
D02.065.064.150.400 Hydroxyacetylaminofluorene
D02.065.064.189 Allylisopropylacetamide 1
D02.065.064.294 Benzeneacetamides 2
D02.065.064.400 Iodoacetamide 2
D02.065.064.416 Lacosamide 3
D02.065.064.432 Levetiracetam 34
D02.065.064.463 Linezolid 17
D02.065.064.525 Oseltamivir 53
D02.065.064.650 Piracetam 88
D02.065.064.786 Thioacetamide 13
D02.241 Carboxylic Acids 244
D02.241.081 Acids, Acyclic 1
D02.241.081.018 Acetates 327
D02.241.081.018.110 Acetamides 133
D02.241.081.018.110.080 2-Acetylaminofluorene 6
D02.241.081.018.110.080.070 Acetoxyacetylaminofluorene 2
D02.241.081.018.110.080.400 Hydroxyacetylaminofluorene
D02.241.081.018.110.189 Allylisopropylacetamide 1
D02.241.081.018.110.400 Iodoacetamide 2
D02.241.081.018.110.432 Lacosamide 3
D02.241.081.018.110.463 Levetiracetam 34
D02.241.081.018.110.525 Linezolid 17
D02.241.081.018.110.650 Piracetam 88
D02.241.081.018.110.786 Thioacetamide 13
D02.455 Hydrocarbons 139
D02.455.426 Hydrocarbons, Cyclic 24
D02.455.426.559 Hydrocarbons, Aromatic 50
D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons 468
D02.455.426.559.847.389 Fluorenes 113
D02.455.426.559.847.389.050 2-Acetylaminofluorene 6
D02.455.426.559.847.389.050.060 Acetoxyacetylaminofluorene 2
D02.455.426.559.847.389.050.400 Hydroxyacetylaminofluorene
D02.455.426.559.847.389.650 Lumefantrine
D02.455.426.559.847.389.850 Tilorone 2
D04 Polycyclic Compounds 65
D04.615 Polycyclic Aromatic Hydrocarbons 468
D04.615.389 Fluorenes 113
D04.615.389.050 2-Acetylaminofluorene 6
D04.615.389.050.060 Acetoxyacetylaminofluorene 2
D04.615.389.050.400 Hydroxyacetylaminofluorene
D04.615.389.650 Lumefantrine
D04.615.389.850 Tilorone 2

3-acetylaminofluorene Chemical MeSH Browser

Add

Narrower terms