2-Acetylaminofluorene [2-acetylaminofluoren]
topical
6
- Terms
-
2-AAF
acetylaminofluoren
-
2-AAF
2-Acetamidofluorene
2-Fluorenylacetamide
AAF, Aminofluorene
Acetylaminofluorene
Fluoren-2-ylacetamide
N-2-Fluorenylacetamide
N-Acetyl-2-Aminofluorene
Persistent link
https://www.medvik.cz/link/D015073
Definition
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
- DUI
- D015073 MeSH Browser
- CUI
- M0023186
- CAS
- Acetamide, N-9H-fluoren-2-yl-
- Previous indexing
- Fluorenes (1966-1974); Acetamides (1971-1974)
- History note
- 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
- Online note
- use 2-ACETYLAMINOFLUORENE to search ACETYLAMINOFLUORENE 1975-82
- Public note
- 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 1
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 3
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D02.065.064.150.400
Hydroxyacetylaminofluorene
D02.241.081.018.110.080.400
Hydroxyacetylaminofluorene
D02.455.426.559.847.389.050.400
Hydroxyacetylaminofluorene
D02.455.426.559.847.389.650
Lumefantrine
D04.615.389.050.400
Hydroxyacetylaminofluorene
D04.615.389.650
Lumefantrine