4-Hydroxycoumarins [4-hydroxykumariny]

topical
18
Persistent link   https://www.medvik.cz/link/D015110
Definition

Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants.

Annotation
/biosyn permitted if by plant
DUI
D015110 MeSH Browser
CUI
M0023241
Previous indexing
Coumarins (1972-1976)
History note
77
Public note
77; PHENPROCOUMON was see under COUMARINS 1975-76

Allowable subheadings

AD
administration & dosage
AE
adverse effects 1
AG
agonists
AN
analysis 6
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood 1
CF
cerebrospinal fluid
CS
chemical synthesis 1
CH
chemistry 5
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification 2
ME
metabolism 1
PK
pharmacokinetics 2
PD
pharmacology 2
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 2
TO
toxicity 4
UR
urine

D Chemicals and Drugs
D03 Heterocyclic Compounds 189
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.663 Pyrans 43
D03.383.663.283 Benzopyrans 62
D03.383.663.283.446 Coumarins 242
D03.383.663.283.446.139 Aminocoumarins 1
D03.383.663.283.446.280 Chromonar
D03.383.663.283.446.350 Coumestrol 5
D03.383.663.283.446.400 Esculin 4
D03.383.663.283.446.520 4-Hydroxycoumarins 18
D03.383.663.283.446.520.079 Acenocoumarol 4
D03.383.663.283.446.520.203 Dicumarol 20
D03.383.663.283.446.520.451 Ethyl Biscoumacetate 23
D03.383.663.283.446.520.750 Phenprocoumon 2
D03.383.663.283.446.520.914 Warfarin 979
D03.383.663.283.446.794 Furocoumarins 34
D03.383.663.283.446.800 Isocoumarins 1
D03.383.663.283.446.853 Pyranocoumarins 1
D03.383.663.283.446.912 Umbelliferones 14
D03.633 Heterocyclic Compounds, Fused-Ring
D03.633.100 Heterocyclic Compounds, 2-Ring 24
D03.633.100.150 Benzopyrans 62
D03.633.100.150.446 Coumarins 242
D03.633.100.150.446.139 Aminocoumarins 1
D03.633.100.150.446.280 Chromonar
D03.633.100.150.446.350 Coumestrol 5
D03.633.100.150.446.400 Esculin 4
D03.633.100.150.446.520 4-Hydroxycoumarins 18
D03.633.100.150.446.520.079 Acenocoumarol 4
D03.633.100.150.446.520.203 Dicumarol 20
D03.633.100.150.446.520.451 Ethyl Biscoumacetate 23
D03.633.100.150.446.520.750 Phenprocoumon 2
D03.633.100.150.446.520.914 Warfarin 979
D03.633.100.150.446.794 Furocoumarins 34
D03.633.100.150.446.800 Isocoumarins 1
D03.633.100.150.446.853 Pyranocoumarins 1
D03.633.100.150.446.912 Umbelliferones 14

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