The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.

DUI

D015230 MeSH Prohlížeč

CUI

M0023403

CAS

Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9alpha,13E,15S)-

Předchozí užití

Prostaglandins (1966-1977); Prostaglandins D (1978-1988)

Historická pozn.

89

Veřejná pozn.

89