The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.

DUI

D015230 MeSH Browser

CUI

M0023403

CAS

Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9alpha,13E,15S)-

Previous indexing

Prostaglandins (1966-1977); Prostaglandins D (1978-1988)

History note

89

Public note

89