Chloramphenicol O-Acetyltransferase [chloramfenikol-O-acetyltransferasa]
topical
4
- Terms
-
chloramfenikol-O-acetyltransferáza
chloramfenikolacetyltransferáza
enzym CAT
-
CAT Enzyme
Chloramphenicol Acetyltransferase
Chloramphenicol Transacetylase
Persistent link
https://www.medvik.cz/link/D015500
Definition
An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
- DUI
- D015500 MeSH Browser
- CUI
- M0023862
- CAS
- Acetyl-CoA-chloramphenicol 3-O-acetyltransferase
- Previous indexing
- Transferases (1966-1972); Acetyltransferases (1973-1988)
- History note
- 1998(1989)
- Public note
- 1998; see CHLORAMPHENICOL ACETYLTRANSFERASE 1989-1997
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.050.134.029
Acyl-Carrier Protein S-Acetyltransferase
D08.811.913.050.134.375
Glucosamine 6-Phosphate N-Acetyltransferase
D08.811.913.050.134.423
N-Terminal Acetyltransferases
D08.811.913.050.134.700
Phosphate Acetyltransferase