Giant Cells [obrovské buňky]
- Terms
-
obří vícejaderné buňky
obrovské mnohojaderné buňky
obrovské vícejaderné buňky
polykaryocyty
syncytium
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Giant Cells, Multinucleated
Multinucleated Giant Cells
Polykaryocytes
Syncytia
Syncytium
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
- DUI
- D015726 MeSH Browser
- CUI
- M0024113
- Previous indexing
- Cell Fusion (1972-1989)
- History note
- 90
- Public note
- 90
Allowable subheadings
- CH
- chemistry 1
- CL
- classification
- CY
- cytology 2
- DE
- drug effects 2
- EN
- enzymology
- IM
- immunology 1
- ME
- metabolism 1
- MI
- microbiology
- PS
- parasitology
- PA
- pathology 21
- PH
- physiology
- RE
- radiation effects 1
- TR
- transplantation
- UL
- ultrastructure 2
- VI
- virology 1