An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

DUI

D016178 MeSH Prohlížeč

CUI

M0024695

CAS

Colony-stimulating factor 2

Předchozí užití

Colony-Stimulating Factors (1976-1990); Growth Substances (1966-1990); Interleukin-3 (1981-1987)

Historická pozn.

91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91

Online pozn.

use INTERLEUKIN-3 to search HISTAMINE-PRODUCING CELL-STIMULATING FACTOR 1987-91

Veřejná pozn.

91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91