Transforming Growth Factor beta [transformující růstový faktor beta]
- Terms
-
TGF-beta
-
Bone-Derived Transforming Growth Factor
Milk Growth Factor
Platelet Transforming Growth Factor
TGF-beta
TGFbeta
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
- DUI
- D016212 MeSH Browser
- CUI
- M0024757
- Previous indexing
- Peptides (1983-1988); Transforming Growth Factors (1989-1990)
- History note
- 91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
- Online note
- use TRANSFORMING GROWTH FACTORS to search TRANSFORMING GROWTH FACTOR BETA & TGF-BETA 1989-90
- Public note
- 91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 7
- AG
- agonists 1
- AN
- analysis 15
- AI
- antagonists & inhibitors 6
- BI
- biosynthesis 7
- BL
- blood 17
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification
- DF
- deficiency 1
- DE
- drug effects 6
- EC
- economics
- GE
- genetics 36
- HI
- history
- IM
- immunology 12
- IP
- isolation & purification 3
- ME
- metabolism 66
- PK
- pharmacokinetics
- PD
- pharmacology 19
- PH
- physiology 24
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 7
- TO
- toxicity 1
- UR
- urine
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