A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

DUI

D016670 MeSH Browser

CUI

M0025401

CAS

Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester

Previous indexing

Protease Inhibitors (1979-1989); Anticoagulants (1966-1991); Guanidines (1966-1991); Serine Proteinase Inhibitors (1990-1991)

History note

92; was GABEXATE (NM) 1976-91

Online note

use GABEXATE (NM) to search GABEXATE 1979-91

Public note

92; GABEXATE was indexed under GUANIDINES 1976-91