An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.

Annotation

MITOMYCINS is also available

DUI

D016685 MeSH Browser

CUI

M0013948

CAS

Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-

Previous indexing

Mitomycins (1966-1991)

History note

2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991

Public note

2000; see MITOMYCIN C 1992-1999; MITOMYCIN C was indexed under MITOMYCINS 1981-1990