ISCOMs [imunostimulační komplex]
- Terms
-
imunostimulační vakcíny (ISCOMs)
-
Immuno-Stimulating Complexes
Immunostimulating Complexes
ISCOM
A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines.
- Annotation
- coord IM with specific type of vaccine (IM or NIM)
- DUI
- D016882 MeSH Browser
- CUI
- M0025686
- Previous indexing
- Adjuvants, Immunologic (1985-1991); Viral Vaccines (1985-1991)
- History note
- 92
- Public note
- 92
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 0
- AN
- analysis 0
- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CH
- chemistry 0
- CL
- classification 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 2
- HI
- history 0
- IM
- immunology 2
- IP
- isolation & purification 1
- ME
- metabolism 0
- PD
- pharmacology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 5
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0