Interferon-alpha [interferon alfa]
- Terms
-
IFN-alfa
INFalfa
interferon leukocytový
interferon lymfoblastický
-
alpha-Interferon
IFN-alpha D
IFN-alpha5
Interferon Alfa
Interferon alpha-1
Interferon alpha-17
Interferon alpha-4
Interferon alpha-5
Interferon alpha-7
Interferon alpha-88
Interferon alpha-J
Interferon alpha-T
Interferon alpha4
Interferon alpha5
Interferon, alpha
Interferon, Leukocyte
Interferon, Lymphoblast
Interferon, Lymphoblastoid
Leif D
LeIF I
LeIF J
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
- DUI
- D016898 MeSH Browser
- CUI
- M0025711
- Previous indexing
- Interferon Type I (1983-1991)
- History note
- 1992; for INTERFERON, LYMPHOBLAST and INTERFERON, LEUKOCYTE use INTERFERON TYPE I 1989-1991
- Public note
- 1992; see INTERFERON TYPE I 1983-1991, INTERFERON ALPHA-1 was indexed under INTERFERON-ALPHA 2001-2011, INTERFERON-ALPHA 2 was indexed under INTERFERON-ALPHA 1997-2011, INTERFERON ALPHA4 was indexed under INTERFERON-ALPHA 1993-2001, INTERFERON ALPHA5 was indexed under INTERFERON-ALPHA 1996-2001
Allowable subheadings
- AD
- administration & dosage 259
- AE
- adverse effects 121
- AG
- agonists 0
- AN
- analysis 3
- AI
- antagonists & inhibitors 5
- BI
- biosynthesis 3
- BL
- blood 4
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 6
- CL
- classification 2
- DF
- deficiency 0
- DE
- drug effects 5
- EC
- economics 4
- GE
- genetics 8
- HI
- history 2
- IM
- immunology 27
- IP
- isolation & purification 2
- ME
- metabolism 9
- PK
- pharmacokinetics 14
- PD
- pharmacology 107
- PH
- physiology 9
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 1
- SD
- supply & distribution 0
- TU
- therapeutic use 548
- TO
- toxicity 4
- UL
- ultrastructure 0
- UR
- urine 0