A moderately malignant neoplasm composed of primitive neuroectodermal cells dispersed in myxomatous or fibrous stroma intermixed with mature ganglion cells. It may undergo transformation into a neuroblastoma. It arises from the sympathetic trunk or less frequently from the adrenal medulla, cerebral cortex, and other locations. Cervical ganglioneuroblastomas may be associated with HORNER SYNDROME and the tumor may occasionally secrete vasoactive intestinal peptide, resulting in chronic diarrhea.

Annotation

coordinate with precoordinated organ/neoplasm term

DUI

D018305 MeSH Browser

CUI

M0027539

Previous indexing

Neuroblastoma (1966-1993); Ganglioneuroma (1966-1993)

History note

94

Public note

94