Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).

Annotation

PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS

DUI

D018620 MeSH Browser

CUI

M0027906

Previous indexing

Prions (1992-1994); Viral Proteins (1989-1991)

History note

95; SCRAPIE AGENT was see PRIONS 1992-94, was heading 1987-91, was SCRAPIE PRION 1986, was SCRAPIE VIRUS 1966-85; SCRAPIE PRP was NM 1988-94; SCRAPIE VIRUS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91, was see SCRAPIE PRION 1986, was heading 1966-85; RIDA VIRUS was see SCRAPIE AGENT 1976-91

Online note

use PRIONS to search SCRAPIE AGENT, SCRAPIE PRION, & SCRAPIE VIRUS 1966-94, and RIDA VIRUS 1976-91; use PRPSC PROTEINS (NM) to search SCRAPIE PRP 1988-94

Public note

95; SCRAPIE AGENT was see PRIONS 1992-94, was heading 1987-91, was SCRAPIE PRION 1986, was SCRAPIE VIRUS 1966-85; SCRAPIE PRP was indexed under PRIONS 1992-94 & VIRAL PROTEINS 1989-91; SCRAPIE VIRUS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91, was see SCRAPIE PRION 1986, was heading 1966-85; RIDA VIRUS was see SCRAPIE AGENT 1976-91