A state arrived at through prolonged and strong contraction of a muscle. Studies in athletes during prolonged submaximal exercise have shown that muscle fatigue increases in almost direct proportion to the rate of muscle glycogen depletion. Muscle fatigue in short-term maximal exercise is associated with oxygen lack and an increased level of blood and muscle lactic acid, and an accompanying increase in hydrogen-ion concentration in the exercised muscle.

Annotation

note category

DUI

D018763 MeSH Browser

CUI

M0028097

Previous indexing

Muscles (1966-1994); Fatigue (1966-1994); specific muscle (1966-1994)

History note

95

Public note

95