Polymorphism, Single-Stranded Conformational [polymorfismus konformace jednovláknové DNA]

topical
36
Terms

polymorfismus konformace jednoduchých řetězců
polymorfismus konformace jednořetězcové DNA
polymorfismus, konformace jednořetězců
SSCP

 

Single-Stranded Conformational Polymorphism
SSCP

Persistent link   https://www.medvik.cz/link/D018807
Definition

Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.

Annotation
POLYMORPHISM, SINGLE NUCLEOTIDE is also available
DUI
D018807 MeSH Browser
CUI
M0028160
Previous indexing
Polymorphism (Genetics) (1990-1994)
History note
1995
Public note
1995