Polymorphism, Single-Stranded Conformational [polymorfismus konformace jednovláknové DNA]
- Terms
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polymorfismus konformace jednoduchých řetězců
polymorfismus konformace jednořetězcové DNA
polymorfismus, konformace jednořetězců
SSCP
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Single-Stranded Conformational Polymorphism
SSCP
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
- Annotation
- POLYMORPHISM, SINGLE NUCLEOTIDE is also available
- DUI
- D018807 MeSH Browser
- CUI
- M0028160
- Previous indexing
- Polymorphism (Genetics) (1990-1994)
- History note
- 1995
- Public note
- 1995
Allowable subheadings