Troponin I [troponin I]
- Terms
-
Troponin I1
Troponin I2
Troponin I3
Troponin-I
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
- Annotation
- TROPONIN C & TROPONIN T are also available
- k dispozici jsou i deskriptory TROPONIN C a TROPONIN T
- DUI
- D019210 MeSH Browser
- CUI
- M0028614
- Previous indexing
- Muscle Proteins (1975-1978); Troponin (1979-1996)
- History note
- 97; was TROPONIN I (NM) 1975-96
- Online note
- use TROPONIN I (NM) to search TROPONIN I 1980-96
- Public note
- 97; TROPONIN I was indexed under TROPONIN 1979-96 & MUSCLE PROTEINS 1975-78
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects 3
- AG
- agonists
- AN
- analysis 32
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood 77
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 3
- HI
- history
- IM
- immunology
- IP
- isolation & purification 7
- ME
- metabolism 10
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards 3
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity 1
- UL
- ultrastructure
- UR
- urine
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TNNI2 protein, human Chemical MeSH Browser
TNNI3 protein, human Chemical MeSH Browser
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