Tissue Inhibitor of Metalloproteinase-2 [tkáňový inhibitor metaloproteinasy 2]
- Terms
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metaloproteinasa 2 - tkáňový inhibitor
TIMP2
tkáňový inhibitor metaloproteinázy 2
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TIMP-2
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.
- DUI
- D019716 MeSH Browser
- CUI
- M0029272
- Previous indexing
- Neoplasm Proteins (1989-1993); Proteins (1990-1997)
- History note
- 1998; see TISSUE INHIBITOR OF METALLOPROTEINASE-2 (NM) 1989-1997
- Public note
- 1998; TISSUE INHIBITOR OF METALLOPROTEINASE 2 was indexed under PROTEINS 1990-97 & NEOPLASM PROTEINS 1989-1993
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis 3
- BL
- blood 3
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 7
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine 1
111In-DTPA-N-TIMP-2 Chemical MeSH Browser
TIMP2 protein, human Chemical MeSH Browser
Timp2 protein, mouse Chemical MeSH Browser
Timp2 protein, rat Chemical MeSH Browser