15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [kyselina 15-hydroxy-11 alfa,9 alfa-(epoxymethano)prosta-5,13-dienová]

topical
1
Terms

(15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid
(15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
11 alpha,9 alpha-Epoxymethano PGH2
9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha
9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha
9,11-epoxymethano-PGH2
U-44619
U-46619
U44619
U46619

Persistent link   https://www.medvik.cz/link/D019796
Definition

A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)

DUI
D019796 MeSH Browser
CUI
M0029372
CAS
5-Heptenoic Acid, 7-(6-(3-Hydroxy-1-Ocentyl)-2-Oxabicyclo(2.2.1)hept-5-yl)-, (1R-(1alpha,4alpha,5 beta(Z),6alpha(1E,3S*)))-
Previous indexing
Prostaglandin Endoperoxides, Synthetic (1978-1997); Thromboxane A2/analogs & derivatives (1983-1997)
History note
1998; use 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID (NM) 1977-1997; for (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 use PROSTAGLANDIN H2 (NM) 1992-2003
Public note
1998; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID was indexed under PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1978-97 & THROMBOXANE A2/analogs & derivatives 1983-97; (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 were indexed under PROSTAGLANDINS H 1993-2003 & PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1986-1992

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology 1
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D01.248 Electrolytes 378
D01.248.497 Ions 434
D01.248.497.158 Anions 82
D01.248.497.158.685 Oxides 152
D01.248.497.158.685.750 Peroxides 93
D01.248.497.158.685.750.744 Prostaglandin Endoperoxides 2
D01.248.497.158.685.750.744.650 Prostaglandins H 2
D01.248.497.158.685.750.744.650.500 Prostaglandin H2
D01.248.497.158.685.750.744.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D01.339 Free Radicals 861
D01.339.431 Reactive Oxygen Species 1 017
D01.339.431.374 Peroxides 93
D01.339.431.374.744 Prostaglandin Endoperoxides 2
D01.339.431.374.744.650 Prostaglandins H 2
D01.339.431.374.744.650.500 Prostaglandin H2
D01.339.431.374.744.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D01.650 Oxygen Compounds 3
D01.650.550 Oxides 152
D01.650.550.750 Peroxides 93
D01.650.550.750.700 Prostaglandin Endoperoxides 2
D01.650.550.750.700.650 Prostaglandins H 2
D01.650.550.750.700.650.500 Prostaglandin H2
D01.650.550.750.700.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D02 Organic Chemicals 391
D02.389 Free Radicals 861
D02.389.593 Reactive Oxygen Species 1 017
D02.389.593.374 Peroxides 93
D02.389.593.374.744 Prostaglandin Endoperoxides 2
D02.389.593.374.744.650 Prostaglandins H 2
D02.389.593.374.744.650.500 Prostaglandin H2
D02.389.593.374.744.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D10 Lipids 2 532
D10.251 Fatty Acids 1 439
D10.251.355 Fatty Acids, Unsaturated 475
D10.251.355.255 Eicosanoids 96
D10.251.355.255.550 Prostaglandins 665
D10.251.355.255.550.025 Prostaglandin Endoperoxides 2
D10.251.355.255.550.025.650 Prostaglandins H 2
D10.251.355.255.550.025.650.500 Prostaglandin H2
D10.251.355.255.550.025.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D23 Biological Factors 143
D23.469 Inflammation Mediators 326
D23.469.050 Autacoids 3
D23.469.050.175 Eicosanoids 96
D23.469.050.175.725 Prostaglandins 665
D23.469.050.175.725.025 Prostaglandin Endoperoxides 2
D23.469.050.175.725.025.650 Prostaglandins H 2
D23.469.050.175.725.025.650.500 Prostaglandin H2
D23.469.050.175.725.025.650.500.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1
D23.469.700 Prostaglandins, Synthetic 38
D23.469.700.630 Prostaglandin Endoperoxides, Synthetic 2
D23.469.700.630.500 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid 1

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