Stabilní analog prostaglandin endoperoxidu, který slouží jako thromboxanové mimetikum. Mezi jeho činnosti patří napodobování hydroosmotického účinku vazopresinu a aktivace fosfolipáz typu C.

A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)

DUI

D019796 MeSH Prohlížeč

CUI

M0029372

CAS

5-Heptenoic Acid, 7-(6-(3-Hydroxy-1-Ocentyl)-2-Oxabicyclo(2.2.1)hept-5-yl)-, (1R-(1alpha,4alpha,5 beta(Z),6alpha(1E,3S*)))-

Předchozí užití

Prostaglandin Endoperoxides, Synthetic (1978-1997); Thromboxane A2/analogs & derivatives (1983-1997)

Historická pozn.

1998; use 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID (NM) 1977-1997; for (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 use PROSTAGLANDIN H2 (NM) 1992-2003

Veřejná pozn.

1998; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID was indexed under PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1978-97 & THROMBOXANE A2/analogs & derivatives 1983-97; (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 were indexed under PROSTAGLANDINS H 1993-2003 & PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1986-1992