Cholesterol Side-Chain Cleavage Enzyme [enzym štěpící postranní řetězce cholesterolu]
- Terms
-
20,22-desmolasa
20,22-desmoláza
cholesteroldesmolasa
cholesteroldesmoláza
CYP 11A1
cytochrom P-450 11A1
cytochrom P-450(scc)
cytochrom P-450(SCC)
cytochrom P450scc
-
20,22-Desmolase
Cholesterol Desmolase
Cholesterol Monooxygenase (Side-Chain-Cleaving)
CYP 11A1
CYP11A1
Cytochrome P-450 CYP11A1
Cytochrome P-450(scc)
Cytochrome P450 11A1
Cytochrome P450scc
A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
- DUI
- D002786 MeSH Browser
- CUI
- M0004271
- CAS
- Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
- Previous indexing
- Multienzyme Complexes (1973-1974); Cholesterol (1971-1974); Oxidoreductases (1971-1974)
- History note
- 2003 (1975)
- Public note
- 2003; see CHOLESTEROL MONOOXYGENASE 1997-2002, see CHOLESTEROL DESMOLASE 1988-1996, see OXIDOREDUCTASES 1975-1987
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 4
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
cyp11a2 protein, zebrafish Chemical MeSH Browser