Aromatase [aromatasa]
- Terms
-
aromatáza
CYP 19
CYP19
cytochrom P-450 CYP19
cytochrom P-450(AROM)
cytochrom P450 19
P450AROM
protein CYP19
-
Androstenedione Aromatase
CYP 19
CYP19
CYP19 Protein
Cytochrome P-450 CYP19
Cytochrome P-450(AROM)
Cytochrome P450 19
Estrogen Synthase
Estrogen Synthetase
P450AROM
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
- DUI
- D001141 MeSH Browser
- CUI
- M0001707
- Previous indexing
- Androstanes (1972-1974); Estrogens (1972-1974); Oxidoreductases (1972-1974)
- History note
- 86(75); was see under OXIDOREDUCTASES 1975-85
- Public note
- 86; was see under OXIDOREDUCTASES 1975-85
Combination
- antagonists & inhibitors
- Aromatase Inhibitors
Allowable subheadings
- AD
- administration & dosage 6
- AE
- adverse effects
- AN
- analysis 6
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 9
- CL
- classification
- DF
- deficiency 5
- DE
- drug effects 3
- EC
- economics
- GE
- genetics 8
- HI
- history 1
- IM
- immunology 1
- IP
- isolation & purification 1
- ME
- metabolism 9
- PK
- pharmacokinetics
- PD
- pharmacology 9
- PH
- physiology 7
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 6
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
CYP19A1 protein, human Chemical MeSH Browser
CYP19A1 protein, rat Chemical MeSH Browser
Cyp19a1 protein, Xenopus Chemical MeSH Browser
Cyp19a1 protein, mouse Chemical MeSH Browser
Cyp19a1a protein, zebrafish Chemical MeSH Browser
Cyp19a1b protein, zebrafish Chemical MeSH Browser