cholesterol-24-hydroxylasa [Cholesterol 24-Hydroxylase]

tematický
Termíny

cholestantetrol-24-hydroxylasa
cholesterol-24-hydroxyláza
CYP46A1
cytochrom P450 46A1

 

5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Brain-Specific 24S-Hydroxylase
Cholestane Tetrol 24-Hydroxylase
CYP46A1
Cytochrome P450 46A1

Perzistentní odkaz   https://www.medvik.cz/link/D000072556
Definice

Steroidní hydroxyláza, která se účastní homeostázy cholesterolu v mozku. Přeměňuje cholesterol na 24S-hydroxycholesterol, který je transportován přes hematoencefalickou bariéru rychleji než nemetabolizovaný cholesterol.

A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.

DUI
D000072556 MeSH Prohlížeč
CUI
M0333121
Historická pozn.
2017 (1999)
Veřejná pozn.
2017; CHOLESTEROL 24-HYDROXYLASE was indexed under STEROID HYDROXYLASES 1999-2016

Povolená podhesla

AN
analýza
AI
antagonisté a inhibitory
AD
aplikace a dávkování
BI
biosyntéza
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie
PH
fyziologie
GE
genetika
IM
imunologie
IP
izolace a purifikace
CL
klasifikace
BL
krev
ME
metabolismus
UR
moč
CF
mozkomíšní mok
DF
nedostatek
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití
TO
toxicita
DE
účinky léků
RE
účinky záření
UL
ultrastruktura
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.244 cytochromy 121
D08.244.453 systém (enzymů) cytochromů P-450 692
D08.244.453.875 rodina 46 cytochromů P450
D08.244.453.875.500 cholesterol-24-hydroxylasa
D08.244.453.915 steroidhydroxylasy 16
D08.244.453.915.025 cholesterol-24-hydroxylasa
D08.244.453.915.050 cytochrom P450 CYP11B2 11
D08.244.453.915.099 aromatasa 72
D08.244.453.915.149 cytochrom P450 CYP271 4
D08.244.453.915.200 cholesterol-7-alfa-hydroxylasa 19
D08.244.453.915.212 enzym štěpící postranní řetězce cholesterolu 6
D08.244.453.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 3
D08.244.453.915.730 steroid-12-alfa-hydroxylasa 1
D08.244.453.915.737 steroid-16-alfa-hydroxylasa 5
D08.244.453.915.748 steroid-17-alfa-hydroxylasa 21
D08.244.453.915.750 steroid-11-beta-hydroxylasa 3
D08.244.453.915.760 steroid-21-hydroxylasa 63
D08.244.453.915.880 sterol-14-demethylasa 2
D08.811 enzymy 1 547
D08.811.682 oxidoreduktasy 446
D08.811.682.690 oxygenasy 76
D08.811.682.690.708 oxygenasy se smíšenou funkcí 68
D08.811.682.690.708.170 systém (enzymů) cytochromů P-450 692
D08.811.682.690.708.170.497 rodina 46 cytochromů P450
D08.811.682.690.708.170.497.500 cholesterol-24-hydroxylasa
D08.811.682.690.708.170.915 steroidhydroxylasy 16
D08.811.682.690.708.170.915.025 cholesterol-24-hydroxylasa
D08.811.682.690.708.170.915.050 cytochrom P450 CYP11B2 11
D08.811.682.690.708.170.915.099 aromatasa 72
D08.811.682.690.708.170.915.150 cytochrom P450 CYP271 4
D08.811.682.690.708.170.915.200 cholesterol-7-alfa-hydroxylasa 19
D08.811.682.690.708.170.915.212 enzym štěpící postranní řetězce cholesterolu 6
D08.811.682.690.708.170.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 3
D08.811.682.690.708.170.915.730 steroid-12-alfa-hydroxylasa 1
D08.811.682.690.708.170.915.737 steroid-16-alfa-hydroxylasa 5
D08.811.682.690.708.170.915.748 steroid-17-alfa-hydroxylasa 21
D08.811.682.690.708.170.915.750 steroid-11-beta-hydroxylasa 3
D08.811.682.690.708.170.915.760 steroid-21-hydroxylasa 63
D08.811.682.690.708.170.915.880 sterol-14-demethylasa 2
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 577
D12.776.422 hemoproteiny 16
D12.776.422.220 cytochromy 121
D12.776.422.220.453 systém (enzymů) cytochromů P-450 692
D12.776.422.220.453.875 rodina 46 cytochromů P450
D12.776.422.220.453.875.500 cholesterol-24-hydroxylasa
D12.776.422.220.453.915 steroidhydroxylasy 16
D12.776.422.220.453.915.025 cholesterol-24-hydroxylasa
D12.776.422.220.453.915.050 cytochrom P450 CYP11B2 11
D12.776.422.220.453.915.099 aromatasa 72
D12.776.422.220.453.915.150 cytochrom P450 CYP271 4
D12.776.422.220.453.915.200 cholesterol-7-alfa-hydroxylasa 19
D12.776.422.220.453.915.212 enzym štěpící postranní řetězce cholesterolu 6
D12.776.422.220.453.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 3
D12.776.422.220.453.915.730 steroid-12-alfa-hydroxylasa 1
D12.776.422.220.453.915.737 steroid-16-alfa-hydroxylasa 5
D12.776.422.220.453.915.748 steroid-17-alfa-hydroxylasa 21
D12.776.422.220.453.915.750 steroid-11-beta-hydroxylasa 3
D12.776.422.220.453.915.760 steroid-21-hydroxylasa 63
D12.776.422.220.453.915.880 sterol-14-demethylasa 2

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