Cholesterol 24-Hydroxylase [cholesterol-24-hydroxylasa]
- Terms
-
cholestantetrol-24-hydroxylasa
cholesterol-24-hydroxyláza
CYP46A1
cytochrom P450 46A1
-
5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Brain-Specific 24S-Hydroxylase
Cholestane Tetrol 24-Hydroxylase
CYP46A1
Cytochrome P450 46A1
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
- DUI
- D000072556 MeSH Browser
- CUI
- M0333121
- History note
- 2017 (1999)
- Public note
- 2017; CHOLESTEROL 24-HYDROXYLASE was indexed under STEROID HYDROXYLASES 1999-2016
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine